This is the combination of IVF (In-Vitro Fertilization) and PGT-A (Preimplantation Genetic Testing for Aneuploidy). PGT-A is a genetic test performed on embryos produced through IVF. PGT-A gives information about embryos’ genetic health to help select the best embryo for transfer and improve your chance of achieving a successful pregnancy. PGT-A was formerly known as PGS, preimplantation genetic screening.
Although the technique has been used for years, IVI currently offers them on regular basis in an effort to secure, even more if possible, the best results in healthy live births. Thanks to the chromosomal screening, the IVF + PGT-A treatment increases the success rates per embryo transfer and it consequently increases the chances of having a healthy baby, following IVI philosophy of “One Healthy Baby at Time”.
Reduced waiting times.
The transfer of the best embryos increases the chances of success. The chances of pregnancy after the first attempt is multiplied, therefore we reduce the need for patients to try more than one cycle.
Lower risk of miscarriage.
PGT-A allows identification of chromosomal unbalances so that only the best embryos are transferred, which significantly reduces the risk of miscarriage.
Increased chances of having a healthy baby.
PGT-A identifies those chromosomally healthy embryos before being transferred, genetically abnormal embryos are discarded.
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IVI is one of the largest fertility providers in the world, with over 65 clinics in 9 countries.
Our fertility clinics offer a personalized diagnosis and a safe procedure to achieve the birth of a healthy baby.
The ovarian stimulation during an IVF + PGT-A treatment consists of injections of hormones that stimulate multiple selection and development of more than one oocyte per cycle with an aim to obtain more than one oocyte for fertilization.
The treatment is performed in assisted reproduction clinics and it takes between 10 to 20 days, depending on the stimulation protocol chosen. Our health professionals will indicate the type of medication and appropriate dosages for each woman, based on each individual case. The patient will self-administer daily injections which contain hormones. During the process, follicle tracking through transvaginal ultrasound scans will be performed and serum oestradiol levels in blood are also measured in order to control ovarian follicular growth and maturation.
When the follicles have reached an appropriate size, the egg retrieval is scheduled. An injection of hCG is administered in order to trigger ovulation and, approximately 36 hours after the hCG injection, egg collection takes place.
The patient attends the clinic in order to undergo egg retrieval under light sedation to prevent discomfort. The procedure takes 15 minutes and a gynaecologist, an embryologist and the anaesthesiologist.
The resulting embryos after fertilization of the oocytes are then observed inside the lab and classified according to their morphology and cell division. PGT-A is performed at blastocyst stage, when the embryo is on day 5 or 6 of development. The procedure involves the biopsy of the embryo, by which a few cells are extracted without affecting embryo viability. After biopsy, the embryos are then cryopreserved until the results of the screening are received and decisions can be taken on a reliable manner. Once studied, only healthy embryos will be selected for transfer.
After PGT-A, selected embryos are ready to be transferred into the uterus by passing a catheter designed for the procedure. The embryo transfer is a simple, painless procedure and no sedation is necessary. After a few minutes rest, the patient is allowed to return home.
All unused good quality embryos will be vitrified and stored for a future use without the need to undergo a new stimulation cycle.