95% accuracy in identifying genetic signatures<\/strong> that will help us distinguish between endometria with good and poor prognosis before initiating reproductive treatment.”<\/p>\nEstablishing a prognosis for endometrial implantation<\/h2>\n While displaced endometria outside the implantation window had been previously identified, it did not lead to a significant improvement in pregnancy rates. That’s why this new research provides added value by allowing the identification of endometria with good and poor prognoses<\/strong>. This, in turn, has led to a threefold difference in the risk of endometrial failure in patients with a poor prognosis. This can result in implantation failure or biochemical or clinical miscarriage.<\/p>\nDr. D\u00edaz-Gimeno warns that these are preliminary findings. “Further lines of study are still necessary for patients with poor prognosis endometria. However, being able to distinguish them preventively through the method we presented at ESHRE is the starting point for researching new procedures<\/strong> to improve their diagnosis and treatment. This will avoid the suffering of women and couples due to possible embryo loss, while improving the chances of success in their reproductive processes. These promising results are yet another example of our strong commitment to personalized or precision medicine,” concludes Dr. D\u00edaz-Gimeno.<\/p>\nThe dialogue between the endometrium and the embryo<\/h2>\n In line with research focused on the behaviour of the endometrium<\/strong>, another relevant study has been presented, titled Extracellular vesicles secreted by the maternal endometrium functionally regulate processes related to embryo development and implantation in human blastocysts<\/em>. A “dialogue” between the embryo and the endometrium based on vesicles has been identified. These vesicles are molecules secreted by the endometrium and captured by the embryo.<\/p>\nDr. Hortensia Ferrero, a researcher at the IVI Foundation and supervisor of this study, explains: “The maternal endometrium secretes vesicles<\/strong> that are captured by human embryos. When the content of these vesicles enters the embryo, it regulates molecular mechanisms involved in improving embryonic quality and, consequently, their competence for implantation. These findings demonstrate the importance of the communication system between the maternal endometrium and the embryo through these small vesicles for successful implantation.”<\/p>\nSafer and more comfortable fertility treatments<\/h2>\n Until now, it was believed that performing transfers during the patient’s natural cycle had limitations and resulted in an excessively rigid protocol. Although there have been previous studies that have attempted to delve into this point of the reproductive process, the truth is that their limitations and a small sample size have made it impossible to achieve the necessary certainties to advance in this direction.<\/p>\n
Now, at IVI, we have presented a pioneering study, with a sample of over 3,000 embryos<\/strong>, called A new mNC protocol that allows a 7-day window for FET planning<\/em>, led by Dr. Carlos Alonso, a gynecologist at IVI Madrid. He himself explains that the results are clear: “Embryo transfer can be scheduled if the endometrium is ready when the follicles measure between 13 and 20 millimeters, without altering the clinical outcomes of the process in any way.”<\/p>\nA natural cycle transfer requires minimal medication<\/strong>, making it more comfortable for the patient. Additionally, it improves efficacy and safety, reducing gestational risks such as preeclampsia towards the end of pregnancy. Dr. Alonso concludes, “These findings allow for nearly 7 days of flexibility in the modified natural cycle, which was previously unknown and is highly beneficial as it allows the timing of the transfer to accommodate the personal or work-related needs of the patients. Moreover, this flexibility is also advantageous for assisted reproduction clinics, as it enables fair organization and equitable planning of procedures.”<\/p>\n","protected":false},"excerpt":{"rendered":"The 39th edition of the European Society of Human Reproduction and Embryology (ESHRE) Congress took place from June 25th to 28th in Copenhagen. It is one of the leading global events in reproductive medicine, in which IVI once again had a prominent presence. Topics such as the influence of environmental contaminants on fertility or the… View Article<\/a>","protected":false},"author":42,"featured_media":105651,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[14],"tags":[367,368],"acf":[],"yoast_head":"\nIVI's studies at ESHRE: improving the results of fertility treatments<\/title>\n \n \n \n \n \n \n \n \n \n \n \n \n\t \n\t \n\t \n \n \n \n\t \n\t \n\t \n","yoast_head_json":{"title":"IVI's studies at ESHRE: improving the results of fertility treatments","description":"IVI's studies at ESHRE show the future path of assisted reproduction treatments, to help infertility patients. 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