{"id":102893,"date":"2021-07-08T14:51:30","date_gmt":"2021-07-08T12:51:30","guid":{"rendered":"https:\/\/www.ivi.uk\/?p=102893"},"modified":"2022-10-03T16:44:55","modified_gmt":"2022-10-03T14:44:55","slug":"icsi-ivf-success-rates-risks","status":"publish","type":"post","link":"https:\/\/www.ivi.uk\/blog\/icsi-ivf-success-rates-risks\/","title":{"rendered":"ICSI Explained: Success Rates, Risks and What to Expect"},"content":{"rendered":"<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Sometimes, even the most advanced methods of assisted conception can benefit from an extra helping hand. <\/span><\/span><a href=\"https:\/\/www.ivi.uk\/assisted-reproduction-treatments\/icsi\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Intracytoplasmic Sperm Injection (<\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">)<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> is a procedure that is performed as part of IVF which is designed to remove barriers which can prevent a sperm cell from fertilizing an egg. <\/span><span style=\"vertical-align: inherit;\">For many, particularly those affected by male infertility, it can significantly improve the chances of conception.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">According to the NHS, 1 in 7 couples will have difficulties when trying to conceive a child. <\/span><span style=\"vertical-align: inherit;\">Nearly half of these couples will find that the difficulties originate with the male partner&#8217;s sperm. <\/span><span style=\"vertical-align: inherit;\">This is referred to as <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">male factor infertility<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">. <\/span><span style=\"vertical-align: inherit;\">In these cases, <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> can be performed as part of <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF treatment<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> to increase the chances of achieving a pregnancy. <\/span><span style=\"vertical-align: inherit;\">It is important to remember that ICSI is not for everyone: it will not benefit all patients undergoing fertility treatment but, if <\/span><\/span><a href=\"https:\/\/www.youtube.com\/watch?v=4tR5ajI346g\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">male infertility<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> is identified or there have been previous unsuccessful <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> attempts, then <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> may be recommended to boost the chances of success.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">In this article, we take a closer look at <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> to find out:<\/span><\/span><\/p>\n<ul>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">When is ICSI recommended, and for who?<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">What should I expect if I opt for ICSI?<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Are there any risks involved with ICSI?<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">What are the success rates of ICSI?<\/span><\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">When is ICSI recommended, and for who?<\/span><\/span><\/strong><\/h3>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">As<\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> isn&#8217;t recommended for all patients, it can be added at an additional cost to your routine fertility treatment. <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> is often recommended if:<\/span><\/span><\/p>\n<ul>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">There is low sperm count or poor sperm mobility (poor movement);<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Sperm is abnormally shaped (poor morphology);<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Previous <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> treatments resulted in none or very few fertilized eggs;<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Surgical sperm retrieval is required (due to a medical condition, vasectomy or an extremely low sperm count);<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Embryo testing is being performed, such as <\/span><\/span><a href=\"https:\/\/www.ivi.uk\/assisted-reproduction-treatments\/ivf-genetic-screening\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Pre-Implantation Genetic Testing for Aneuploidy (PGT-A)<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> ;<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Frozen sperm is being used that may be of low quality.<\/span><\/span><\/li>\n<\/ul>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">When undergoing any fertility treatment, it is normal to feel like you want to do everything you can to achieve that positive result. <\/span><span style=\"vertical-align: inherit;\">However, unless a male fertility issue has been identified and diagnosed, <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">your chances of success will be the same with or without ICSI. <\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">If a fertility issue is related to poor egg quality or immature eggs failing to fertilize, then it is an issue which cannot be treated by <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">. <\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">In these cases, you may wish to think about other options such as <\/span><\/span><a href=\"https:\/\/www.ivi.uk\/assisted-reproduction-treatments\/egg-donation\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">egg donation<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">What should I expect if I opt for ICSI?<\/span><\/span><\/strong><\/h3>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Opting for <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI treatment<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> will see you follow exactly the same treatment path as with conventional <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> , but a different fertilization method will be used in the laboratory. <\/span><span style=\"vertical-align: inherit;\">In order to fertilize an egg, the sperm must reach and attach itself to the egg and proceed to push through the harder outer layer of the egg to reach the cytoplasm. <\/span><span style=\"vertical-align: inherit;\">However, if the outer layer of the egg is particularly thick, or if sperm has poor mobility or abnormal morphology, this is where <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> can increase the chances of successful fertilization.\u00a0<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">With conventional <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF,<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> the sperm and the egg are mixed in a petri dish and left to fertilize. <\/span><span style=\"vertical-align: inherit;\">With <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">,<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> an embryologist selects the healthiest sperm and injects the single sperm directly into the center of the egg. <\/span><span style=\"vertical-align: inherit;\">This helps to ensure that fertilization has the highest possible chance of occurring. <\/span><span style=\"vertical-align: inherit;\">It can also bypass any issues the sperm may have in reaching or penetrating the egg. <\/span><span style=\"vertical-align: inherit;\">Embryos are then left to develop for up to five days in a laboratory, before they are selected to be transferred to the womb with the hope of implantation.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Are there any risks involved with ICSI?<\/span><\/span><\/strong><\/h3>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI was <\/span><\/span><a href=\"https:\/\/www.sciencedaily.com\/releases\/2016\/10\/161006101459.htm#:~:text=ICSI%20was%20pioneered%20at%20the,born%20on%2014%20January%201992.\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">first performed in 1987<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> and the technique has since advanced rapidly. <\/span><span style=\"vertical-align: inherit;\">As with any medical treatment, it&#8217;s not without its risks but for many people, the hope of becoming a parent outweighs the rare likelihood of these occurring. <\/span><span style=\"vertical-align: inherit;\">Some of the initial research into <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> found that there is a <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">slightly increased risk of birth defects<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> , however this is at a level similar to conventional IVF. <\/span><span style=\"vertical-align: inherit;\">In both cases, the risk is just slightly higher that of a natural pregnancy in which the chances of a birth defect are between 1.5 and 3 per cent.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">A 2016 study into the first offspring born as a result of <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> found that <\/span><\/span><a href=\"https:\/\/academic.oup.com\/humrep\/article\/31\/12\/2811\/2730248\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">men born using the technique had a lower quantity and quality of sperm<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> in comparison to their naturally-conceived peers. <\/span><span style=\"vertical-align: inherit;\">However, this finding was not surprising to experts given that fertility issues can be hereditary. <\/span><span style=\"vertical-align: inherit;\">In any case, it should be noted that research is limited as the first generation of children born through <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> only reached adulthood in 2010.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">What are the success rates of ICSI?<\/span><\/span><\/strong><\/h3>\n<p><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> is very effective in facilitating fertilization, but it&#8217;s important to remember that this is just one part of the <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> process. <\/span><span style=\"vertical-align: inherit;\">The success rate in terms of a pregnancy and live birth is still tied in with the success rate of the overall <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> treatment. <\/span><span style=\"vertical-align: inherit;\">The UK&#8217;s Human Fertilization &amp; Embryology Authority (HFEA), the organization responsible for governing fertility clinics, doesn&#8217;t report separate <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF with ICSI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> \u00a0success rates, as they are so similar to conventional <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> success rates.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">While many may think that injecting the sperm directly into the egg would result in a 100 per cent success rate, this isn&#8217;t the case. <\/span><span style=\"vertical-align: inherit;\">While it is certainly very effective, <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ICSI treatment<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> achieves successful fertilization in between <\/span><\/span><a href=\"https:\/\/www.whattoexpect.com\/getting-pregnant\/fertility-tests-and-treatments\/high-tech-fertility-treatments\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">50-80 per cent of cases<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> . <\/span><span style=\"vertical-align: inherit;\">The rest is down to the subsequent <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">IVF<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> treatment and the successful implantation of the embryo into the womb lining after being transferred.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Find Out More About ICSI Treatment<\/span><\/span><\/strong><\/h3>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">At IVI London, <\/span><\/span><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ISCI<\/span><\/span><\/strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> is just one of the fertility treatment options we offer to help our patients finally start or grow their families. <\/span><span style=\"vertical-align: inherit;\">Your journey with us will always start with an individual assessment so that we can recommend the fertility treatment that will be most suitable for you. <\/span><span style=\"vertical-align: inherit;\">If you like to learn more, why not attend one of <\/span><\/span><a href=\"https:\/\/www.ivi.uk\/virtual-open-evening\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">our free online information events<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> or <\/span><\/span><a href=\"https:\/\/www.ivi.uk\/ask-for-an-appointment\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">speak to a member of our team<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> \u00a0to find out how we can help you.<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"Sometimes, even the most advanced methods of assisted conception can benefit from an extra helping hand. Intracytoplasmic Sperm Injection (ICSI) is a procedure that is performed as part of IVF which is designed to remove barriers which can prevent a sperm cell from fertilizing an egg. For many, particularly those affected by male infertility, it&#8230; <a class=\"view-article\" href=\"https:\/\/www.ivi.uk\/blog\/icsi-ivf-success-rates-risks\/\">View Article<\/a>","protected":false},"author":1,"featured_media":102906,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[15,17],"tags":[66,220],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.12 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ICSI Explained: Success Rates, Risks and What to Expect - IVI UK<\/title>\n<meta name=\"description\" content=\"ICSI (Intracytoplasmic Sperm Injection) is a fertilisation method performed as part of IVF. 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